We are seeking a highly motivated postdoctoral fellow to join our “Stress in normal and malignant haematopoiesis” team, in the heart of the vibrant London, at the Barts Cancer Institute, Queen Mary University of London.
We will investigate, in collaboration with Dr Ana Rio-Machin’s Lab, the contribution of germline variants to the development of haematological diseases to improve the diagnosis, early detection and management of familial cases, and to unravel new oncogenic mechanisms.
A PhD in biological sciences is essential, as is experience of working with a team in a research environment. An understanding of the research process, high bench skills and a rigorous record of data are essential. Experience in primary mammalian cell culture, haematopoietic assays, RNA biology and flow cytometry are highly desirable.
Recent publication from the Lab:
Vitamin B5 and succinyl-CoA improve ineffective erythropoiesis in SF3B1-mutated myelodysplasia. Sci Transl Med. 2023 Mar;15(685):eabn5135. PMID: 36857430
Germline ERCC excision repair 6 like 2 (ERCC6L2) mutations lead to impaired erythropoiesis and reshaping of the bone marrow microenvironment. Br J Haematol. 2022 Dec;199(5):754-764. PMID: 36156210