Programme
 
Mercredi 12 octobre 2016,

 

17:30 – 19:30 : Enregistrement et cocktail de bienvenue

 

19:30 : Dîner

 

Mercredi 12 octobre 2016 / Session 1
Moderateurs : Olivier Hérault, Pierre Lutz

 

20:30 – 20:45 : Conférence inaugurale :

Olivier Hérault (président du CHO)

 

20:45 – 21:30 : Emmanuelle Passegué (UCSF, San Francisco, USA)

Conférence plénière: "Hematopoietic Stem Cell Function in Stress, Disease and Aging"

 

Jeudi 13 octpobre 2016 Session 2
Moderateurs : Michel Aurrand-Lions, Béatrice Romagnolo

 

8:30 – 9:15  : Triantafyllos Chavakis (Univ Carl Gustav Carus, Dresden, Germany)

Del1 in the hematopoietic stem cell niche

 

9:15 – 9:30 : Christelle Freitas (INSERM UMR 996, Clamart, France)

Impact of a gain-of-function mutation of Cxcr4 on hematopoiesis in mice

 

9:30 – 9:45 : Nicola Sunter (CNRS UMR 7292, Tours, France)

Modelling the Leukaemic Niche in 3D: an evaluation of three potential sources of stromal cells

 

9:45 – 10:00 : Présentations des posters . Session I

 

10:00 – 10:30 : Pause

 

10:30 – 10:45 : Mario Flores Violante (INSERM U1052, CNRS UMR5286, Lyon France)

Identification of the role of the BMP pathway in Acute Myeloid Leukemia (AML) through the correlation with DNp73 and NANOG, themselves associated with leukemic stem cells

 

10:45 – 11:00 : Prashanth Kumar Kandalla (CNRS INSERM CIML, Marseille, France)

M-CSF improves protection against bacterial, fungal and viral infections after hematopoietic stem/progenitor cell transplantation

 

11:00 – 11:45 : Maria Elena Fernandez-Sanchez (Institut Curie, Paris, France)

Mechanosensitivity of  junctional beta-catenin: from mesoderm mechanotransductive evolutionary origins to tumourogenic mechanical induction

 

12:00 : Déjeuner

 

Jeudi 13 octobre 2016 Session 3
Moderateurs : Celio Pouponnot,  Pierre Lutz

 

15:00 – 15:45 : Béatrice Romagnolo (Institut Cochin, Paris, France)

Critical roles for autophagy inhibition in colorectal cancer

 

15:45 – 16:00 : Stéphane Manenti (CRCT, Toulouse, France)

FLT3-ITD receptor induces ATF4-dependent autophagy in acute myeloid leukemia

 

16:00 – 16:15 : Camille Spinner (UMR 5089, CNRS-UPS, IPBS, Toulouse, France)

Role of the ASB2a E3 ubiquitin ligase in tumor development

 

16:15 – 16:30 : Présentations de posters. Session II

 

16:30 – 17:00 : Pause

 

17:00 – 17:15 : Dominique Bluteau (INSERM U944, CNRS UMR 7212, IUH, Paris, France)

FANCV (REV7/MAD2L2), a new Fanconi anemia gene

 

17:15 – 17:30 : Daniela Barbieri (INSERM U1170, IGR, Villejuif, France)

Thrombopoietin restrains retrotransposon-mediated DNA damage in hematopoietic stem cells by promoting an anti-viral innate immune response

 

17:30 – 17:45 : Edwige Voisset (King’s college London, London, UK)

Pml nuclear body disruption cooperates in APL pathogenesis, impacting DNA damage repair pathways

 

17:45 – 18:30 : Bruno Amati (IIT and IEO, Milan, Italy)

Transcriptional programs, genetic modifiers and therapeutic targets in Myc-driven tumors 

 

18:30 : Présentations de posters - pause

 

20:30 : Dîner

Vendredi 14 octobre 2016 Session 4
Moderateurs : Evelyne Lauret, Olivier Herault

 

9:00 – 9:45 : Hana Raslova (Institut Gustave Roussy, Villejuif, France)

Inherited thrombocytopenias predisposing to hematological malignancies

 

9:45 – 10:00 : Lise Secardin (INSERM UMR 1170, IGR, Villejuif, France)

Modélisation des néoplasmes myéloprolifératifs (NMP) mutés pour la calréticuline par génération de cellules souches induites à la pluripotence (iPSC)

 

10:00 – 10:15 : Anna Guadall (INSERM U1131, Paris, France)

Endothelial cells harbouring JAK2V617F mutation display pro-thrombotic characteristics

 

10:15 – 10:45 : Pause

 

10:45 – 11:00 : Lydie Debaize (CNRS UMR 6290, IGDR, Rennes, France)

Two hematopoietic transcription factors, RUNX1 and FUBP1, control jointly the expression of c-KIT oncogene in pre-B lymphoblasts

 

11:00 – 11:15 : Amelle Vandevelde (CNRS UMR7258, INSERM U1068, CRCM, Marseille, France)

Role of PLZF in hematopoietic stem cell stress response

 

11:15 – 12:00 : Philippe Kastner (IGBMC, Strasbourg, France)

Function of Ikaros family transcription factor in hematopoiesis 

 

12:00 : Déjeuner

 

13:30 – 15:30 : Temps libre

 

Vendredi 14 octobre 2016 Session 5
Moderateurs : Thomas Mercher, Laurent Delva

 

15:30 – 16:15 : urg Schwaller (Dept of Biomedicine University Hospital, Basel, Switzerland)

Insights on origin and targets of hematopoietic malignancies by conditional transgenic mouse models

 

16:15 – 16:30 : Anne Largeot (CRUM MI, Manchester, UK)

Identification of new potential therapeutic targets in MOZ- and MLL- related acute myeloblastic leukaemia

 

16:30 – 16:45 : Gaëlle Cordonnier (INSERM U 1151, INEM, Paris, France)

CBFb-SMMHC directly regulates ribosomal gene transcription and alters ribosome biogenesis

 

16:45 – 17:00 : Pause

 

17:00 – 17:15 : Amélie Guitart (SCRM, Edinburgh, UK)

The role of Cited 2 in haematopoiesis regulation

 

17:15 – 17:30 : Anne-Sophie Alary (INSERM U1016, Institut Cochin, Paris, France)

Gene expression and alternative splicing datasets analyses of MDS with ring sideroblasts highlight alternative branchpoint usage in genes involved in iron metabolism and erythropoiesis.

 

17:30 – 18:15 : Jacques Ghysdael (UMR3348 CNRS-Institut Curie, Orsay)

Novel targeted therapies in T cell acute lymphoblastic leukemia

 
Vendredi 14 octobre 2016, 18:15 – 19:00 : Assemblée Générale
 
Vendredi 14 octobre 2016, 20:00 : Dîner
 
Vendredi 14 octobre 2016, 21:00 : Soirée de gala

 

Samedi 15 octobre 2016, Session 6
Moderateurs : Françoise Pflumio, Isabelle André-Schmutz

 

8:30 – 9:15 : Marc Piechaczyk (IGMM, UMR5535 CNRS, Montpellier, France)

The ROS/SUMO axis is involved in the response of chemosensitive acute myeloid leukemia (AML) cells to chemotherapeutics and constitutes a potential target to overcome chemoresistance

 

9:15 – 9:30 : Bochra Zidi (CNRS UMR 7258, INSERM U1068, CRCM, Marseille, France)

Aging-associated defects in hematopoietic differentiation involve redox regulation by the stress protein TP53INP1

 

9:30 – 9:45 : Mathieu Meunier (TIMC-Therex, CNRS UMR 5525, Grenoble, France)

Mechanisms of improvement of erythropoiesis with low dose deferasirox in low risk myelodysplastic syndromes

 

9:45 – 10:00 : Pause

 

10:00 – 10:15 : Coralie Hoarau-Aveila (INSERM U1037, CRCT, Toulouse, France)

Methylated miR-125b gene is a promising biomarker of resistance to chemotherapy in ALK-positive cells with diagnostic potential

 

10:15 – 11:00 : Michael Rieger (LOEWE Center for Cell and Gene Therapy Frankfurt, Germany)

Hematopoietic stem cell self-renewal and differentiation control at single cell resolution

 

11:15 – 11:30 : Remise des prix

Fin du congrès