21e congrès du CHO à Grasse (Alpes Maritimes)
du dimanche 28 sept au mercredi 1er octobre 2014
Programme
Dimanche 28/09/2014. Session 1
Modératrice : Michele Goodhardt
20h30 – 20h45 : Ouverture du congrès :
Véronique Maguer–Satta (Présidente du CHO)
20h45 – 21h30 : Hartmut GEIGER (Ulm, Allemagne)
Keynote lecture: "Hematopoietic stem cell aging: not a one way road"
Lundi 29/09/2014, 9h – 11h45. Session 2
Modérateurs : Eric Soler – Estelle Duprez
9h – 9h45 : Jean-Christophe ANDRAU (IGMM, Montpellier)
"TBA Dynamic of epigenetic landscape and regulatory elements in developing T-cells"
9h45 - 10h : Lauriane Scourzic (INSERM U1009, IGR, Villejuif)
“Oncogenic cooperation between DNA methylation regulators TET2 and DNMT3A in hematopoietic malignancies »
10h - 10h15 : Agata Cieslak ( INSERM U1151, Hôpital Necker, Paris)
« RUNX1, a novel V(D)J recombination cofactor in humans »
10h15 - 10h30 : Pause
10h30 - 10h45 : Christelle Vincent-Fabert (UMR7258, CRCM, Marseille)
« Deciphering PLZF function in hematopoietic stem cells »
10h45 - 11h : Samuel Collombet (INSERM U1024, IBENS, Paris)
« Logical modelling of immune cell specification and reprogramming »
11h - 11h45 : Connie BONIFER (Birmingham, UK)
"Aberrant chromatin programming in acute myeloid leukaemia"
Lundi 29/09/2014, 15h – 18h. Session 3
Modérateurs : Jean Soulier - Thomas Mercher
15h - 15h45 : Alain EYCHENE (Institut Curie, Orsay)
"Raf signaling in mouse melanocyte stem cell and melanoma"
15h45 – 16h : Marie-Pierre Arnaud (CNRS UMR6290, Rennes)
“Disruption of CD9 expression affects adhesion, migration, and actin polymerization through RAC1 signalling pathway in ETV6/RUNX1 pre-B lymphocytes »
16h - 16h15 : Isabel Hidalgo (CNIC, Madrid, Spain)
“Bmi1 controls the hematopoietic stem cell niche maintenance »
16h15 -16h30 : Pause
16h30 – 16h45 : Maria De Grandis (CNRS UMR 7258, CRCM, Marseille)
« JAM-C: a new leukemic stem cell biomarker in Acute Myeloid Leukemia »
16h45 – 17h00 : Xavier Cahu (CEA, Fontenay aux Roses)
“Bone marrow adipocytes negatively imprint on T-cell acute lymphoblastic leukemia development »
17h00- 17h15 : Bastien Laperrousaz (INSERM U1052, CRCL, Lyon)
“Impact of BCR-ABL expression on cell stiffness in a model of immature hematopoietic human cells »
17h15 - 18h : Radek SKODA (Basel, Switzerland)
"Stem cell dynamics and disease initiation in myeloproliferative neoplasms"
Lundi 29/09/2014 : 18h 30 : Apéritif – Poster session
Lundi 29/09/2014 : 20h : Dîner de Gala
Mardi 30/09/2014, 9h – 11h45. Session 4
Modérateurs : Michèle Souyri – Pierre Lutz
9h - 9h45 : Catherine ROBIN (Utrecht, The Netherlands)
"Sequential maturation process towards hematopoietic stem cell production in the mouse embryo"
9h45 - 10h : Carine Halfon-Domenech (CNRS UMR7622, UPMC, Paris)
« Could embryonic haematopoiesis be at the origin of oncogenesis in the Fanconi model? »
10h - 10h15 : Georges Lacaud (CRUK, Manchester, UK)
“GFI1 proteins orchestrate the emergence of haematopoietic stem cells in the AGM through recruitment of LSD1 »
10h15 - 10h30 : Pause
10h30 - 10h45 : Eric Soler (INSERM U967, CEA Fontenay aux Roses)
« Control of developmentally poised erythroid genes by combinatorial corepressor actions »
10h45 - 11h : Thiago Maciel (INSERM UMR1163, Paris)
« An activin receptor IIA ligand trap corrects ineffective erythropoiesis in b-thalassemia »
11h - 11h45 : Katrin OTTERSBACH (Cambridge, UK)
"Dissecting the niche of emerging haematopoietic stem cells"
Mardi 30/09/2014 : 12h : Déjeuner
Mardi 30/09/2014 : 13h30 – 15h15 : Visite Grasse
Mardi 30/09/2014, 15h – 19h. Session 5
Modérateurs : Olivier Hérault, Frédéric Mazurier
15h30 - 16h15 : Laurent YVAN-CHARVET (INSERM U1065, Nice)
"Metabolic abnormalities in wasting syndrome"
16h15 - 16h30 : Urszula Sieranska (INSERM UMR967, CEA, Fontenay aux Roses)
“SCL/TAL1 expression levels modulate human HSPC location and surrounding niche in relation with hypoxia in the bone marrow »
16h30 - 16h45 : Cyril Quivoron (INSERM U985, IGR, Villejuif)
« AG-221, a potent IDH2 R140Q mutant inhibitor, induces terminal differentiation in a xenotransplant model. »
16h45 - 17h : Pause
17h00 - 17h15 : Virginie Chesnais (INSERM U1016, Cochin, Paris)
« Etude de l'architecture clonale des MDS après amplification ex vivo de progéniteurs CD34+CD38-»
17h15 - 17h30 : Marc Piechaczyk (CNRS UMR5535, IGMM, Montpellier)
« The ROS/SUMO axis is involved in chemosensitive acute myeloid leukemia (AML) cells response to chemotherapeutics and constitutes a potential target to overcome chemoresistance in AMLs ».
17h30 – 18h15 : Stéphane Manenti (Toulouse)
"Cell cycle regulation and checkpoints in AML"
Mardi 30/09/2014 : 18h15 - 19h : AG
Mardi 30/09/2014 : 20h : Soirée de Gala
Mercredi 01/10/2014, 8h30 – 11h. Session 6
Modérateurs : Eric Delabesse, Françoise Porteu
8h30 – 9h15 : Jean SOULIER (IUH, Paris)
"Clonal evolution, tumor progression and relapse in leukemia"
9h15 - 9h30 : Marie-Anne Hospital (INSERM U1016, Cochin, Paris)
« Pim kinases modulate resistance to tyrosine kinase inhibitors in FLT3-ITD acute myeloid leukemia »
9h30 - 9h45 : Dorothée Selimoglu-Buet (INSERM U1009, IGR, Villejuif)
“Down-regulation of miR-150 generates the accumulation of classical monocytes, a characteristic feature of chronic myelomonocytic leukemia »
9h45- 10h : Pause
10h – 10h15 : Aurore Hattabi (INSERM U1016, Cochin, Paris)
“Study of the post-transcriptional regulators Pumilio 1/2 in normal and pathologic hematopoietic stem/progenitor cells. »
10h15- 11H : David BRYDER (Lund, Sweden)
"Searching for the target cell in MLL-ENL driven AML"
11h15 – 11h30 : Fin du congrès